To compare measurements of central corneal thickness (CCT) and anterior chamber depth (ACD) obtained using Galilei™, Pentacam® (Oculus, Wetzlar, Germany) and Lenstar® (Haag-Streit, Koeniz, Switzerland) and analyze the measurement agreements.

CCT and ACD were measured using Galilei™, Pentacam® and Lenstar® in 47 eyes of 25 healthy subjects. The measurements were compared among the 3 devices.

The average CCT measurements using Galilei™, Pentacam® and Lenstar® were 552.6 ± 29.41 µm, 543.9 ± 30.50 µm and 537.5 ± 30.26 µm, respectively. The measurements significantly correlated with each other (r > 0.9, p < 0.001), but were statistically significantly different ( p < 0.001). The average ACD measurements using Galilei™, Pentacam® and Lenstar® were 3.23 ± 0.360 mm, 3.22 ± 0.403 mm and 3.19 ± 0.367 mm, respectively. The measurements significantly correlated with each other (r > 0.9, p < 0.001), but were statistically significantly different ( p = 0.034). The CCT 95% limits of agreement (LoA) between Galilei™ and Pentacam®, Pentacam® and Lenstar® and Lenstar® and Galilei™ were 31.95 µm, 44.76 µm and 46.57 µm, respectively and 95% ACD LoA were 0.46 mm, 0.32 mm and 0.28 mm, respectively.

CCT and ACD measured using the 3 devices were highly correlated with each other but the measurements were statistically different. Therefore, the measurements were not interchangeable and these differences should be considered in clinical use.