摘要:Background: The significance of investigating relationships involved in the transport of lipids to the foetus is very important in the first-trimester embryogenesis. The objective of this study, therefore, was to model the relationship between the maternal booking visit lipid profile parameters and the placental indices outcomes. Method: Analytical descriptive cross-sectional study was conducted between March 2014 and October 2018 on placenta, neonates and maternal booking visit lipid profile parameters. A total of 240 pregnant women who attended antenatal care at the Victory Maternity Home and Clinic in Kumasi for the first time and consented to participate were enrolled in the study. Maternal booking lipid profile parameters including; total cholesterol (TC), triglyceride (TG), high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C) were obtained on their first antenatal clinic (ANC) visit. Blood samples were collected from the participants for serum preparation and analysis. Results: The mean value for placental weight in the current study was 502.40 ± 103.70 g (95% CI = 489.20 - 515.60). Mean values of placental diameter and thickness were 19.01 ± 2.41 cm (95% CI of 18.71 - 19.32) and 2.85 ± 0.53 cm (95% CI of 2.78 - 2.92), respectively. All the booking visit lipids, namely TC, TG, HDL-C and LDL-C significantly influenced the placental volume (p < 0.05). Conclusion: It was found that all the maternal booking visit lipids (TC, TG, HDL-C and LDL-C) could jointly predict the outcome of placental volume.
关键词:Lipid ProfilePillai’s Test StatisticLipoproteinBooking VisitPlacentaCholesterolTriglyceride