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标题：Socio-demographic and Haematological Determinants of Breast Cancer in a Tertiary Health Care and Teaching Hospital in Addis Ababa, Ethiopia
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作者：Fatuma Hassen ; Fikre Enquoselassie ; Ahmed Ali 等
期刊名称：Ethiopian Journal of Health Development
印刷版ISSN：1021-6790
出版年度：2021
卷号：35
期号：2
页码：1-8
语种：English
出版社：African Journals Online
摘要：Background: Breast cancer is the major cause of cancer deaths among women globally. Socio-demographic and haematological characteristics are among the determinants of breast cancer, and these characteristics are supposed to be monitored during early diagnosis and treatment of cases.Objective: The objective of this study was to assess socio-demographic and haematological profile of patients with breast cancer at Tikur Anbessa Specialized Hospital.Methods: Case controlled study was conducted among 230 cases and 230 controls from May 2018 to June 2019. Descriptive analysis was made to assess socio-demographic characteristics and independent sample t- test was performed to compare the mean haematological parameters.Results: The mean age was 42.8 + 12.1 years and 39.3 + 11.1 years for cases and controls, respectively. About 43.5% of the cases and 14.8% of the controls were not able to read and write. About 76.1% of the cases and 67.4% of the controls were married. The mean values of Haemoglobin, Red Blood cell, Packed Cell Volume for the cases were 13.1 + 1.6g/dl; 4.6 + 0.54x1012/L; and 38.7 + 4.5 %, respectively. These were significantly lower than those of the controls (14.0 + 1.3g/dl, 4.8 + 0.47 x 1012/L, 40.5 + 3.5%, respectively). Mean platelet count was higher among the cases, whereas total White Blood cell count was almost similar.Conclusion and recommendations: Majority of the cases were less than 40 years of age and were not able to read and write. Most of the RBC parameters of cases were significantly lower than the controls. Therefore, attention should be given for exposed groups and those with the designated haematological abnormalities.
关键词：Breast cancer; Haematological parameters; Socio-demographic factors; Ethiopia