文章基本信息

标题：Risk prediction of biomarkers for early multiple organ dysfunction in critically ill patients
本地全文：下载
作者：Shigeto Ishikawa ; Yuto Teshima ; Hiroki Otsubo 等
期刊名称：BMC Emergency Medicine
印刷版ISSN：1471-227X
电子版ISSN：1471-227X
出版年度：2021
卷号：21
DOI：10.1186/s12873-021-00534-z
语种：English
出版社：BioMed Central
摘要：Background Shock and organ damage occur in critically ill patients in the emergency department because of biological responses to invasion, and cytokines play an important role in their development. It is important to predict early multiple organ dysfunction (MOD) because it is useful in predicting patient outcomes and selecting treatment strategies. This study examined the accuracy of biomarkers, including interleukin (IL)-6, in predicting early MOD in critically ill patients compared with that of quick sequential organ failure assessment (qSOFA). Methods This was a multicenter observational sub-study. Five universities from 2016 to 2018. Data of adult patients with systemic inflammatory response syndrome who presented to the emergency department or were admitted to the intensive care unit were prospectively evaluated. qSOFA score and each biomarker (IL-6, IL-8, IL-10, tumor necrosis factor-α, C-reactive protein, and procalcitonin [PCT
关键词：Critically ill; Interleukin; Multiple organ dysfunction; Predictive marker; qSOFA