文章基本信息

标题：Corneal confocal microscopy demonstrates axonal loss in different courses of multiple sclerosis
本地全文：下载
作者：Ioannis N. Petropoulos ; Kathryn C. Fitzgerald ; Jonathan Oakley 等
期刊名称：Scientific Reports
电子版ISSN：2045-2322
出版年度：2021
卷号：11
DOI：10.1038/s41598-021-01226-1
语种：English
出版社：Springer Nature
摘要：Axonal loss is the main determinant of disease progression in multiple sclerosis (MS). This study aimed to assess the utility of corneal confocal microscopy (CCM) in detecting corneal axonal loss in different courses of MS. The results were confirmed by two independent segmentation methods. 72 subjects (144 eyes) [(clinically isolated syndrome (n = 9); relapsing–remitting MS (n = 20); secondary-progressive MS (n = 22); and age-matched, healthy controls (n = 21)