文章基本信息

标题：Virologic suppression and associated factors in HIV infected Ugandan female sex workers: a cross-sectional study
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作者：Darius Owachi ; Godwin Anguzu ; Joanita Kigozi 等
期刊名称：African Health Sciences
印刷版ISSN：1680-6905
电子版ISSN：1729-0503
出版年度：2021
卷号：21
期号：2
页码：603-613
DOI：10.4314/ahs.v21i2.15
语种：English
出版社：Makerere University Medical School（Uganda)
摘要：Introduction Key populations have disproportionately higher HIV prevalence rates than the general population. Objective To determine the level of virologic suppression and associated factors in female Commercial Sex Workers (CSW) who completed six months of ART and compare with the female general population (GP). Methods Clinical records of CSW and GPs who initiated ART between December 2014 to December 2016 from seven urban clinics were analyzed to determine virologic suppression (viral load < 1000 copies/ml) and associated factors. Results We identified 218 CSW and 182 female GPs. CSW had median age of 28 (IQR 25–31) vs 31 (IQR 26–37); median baseline CD4 446 (IQR 308–696) vs 352 (IQR 164–493) cells/microL; and optimal ART adherence levels at 70.6% vs 92.8% respectively, compared to GP. Virologic suppression in CSW and GPs was 85.7% and 89.6% respectively, P=0.28. Overall virologic suppression in CSW was 55% while Retention in care after 6 months of ART was 77.5%. Immediate ART initiation (<2weeks) and tuberculosis independently predicted virologic suppression in CSW with adjusted odds ratios 0.07 (95% C.I. 0.01–0.55, P=0.01) and 0.09 (95% C.I. 0.01–0.96, P=0.046) respectively. Conclusion Virologic suppression in both groups is similar, however, intensified follow-up is needed to improve treatment outcomes