文章基本信息

标题：Prognostic value of characteristics of plaque combined with residual syntax score among patients with STEMI undergoing primary PCI: an intravascular optical coherence tomography study
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作者：Xiaoxiao Zhao ; Ying Wang ; Runzhen Chen 等
期刊名称：Thrombosis Journal
印刷版ISSN：1477-9560
电子版ISSN：1477-9560
出版年度：2021
卷号：19
DOI：10.1186/s12959-021-00329-z
语种：English
出版社：BioMed Central
摘要：Aim The present study aimed to explore these characteristics, particularly thin-cap fibroatheroma (TCFA), in relation to residual syntax score (rSS) in patients who presented with acute MI. Methods and outcomes A total of 434 consecutive patients with MI aged ≥18 years who had STEMI underwent primary PCI. Notably, compared with other subgroups, the presence of TCFA in culprit lesions and a higher level of rSS, were significantly associated with MACE. When rSS was divided into three groups, high rSS levels were associated with a higher incidence of MACE, in the subgroups of without TCFA ( P = 0.005), plaque erosion ( P = 0.045), macrophage infiltration ( P = 0.026), and calcification ( P = 0.002). AUC of ROC curve was 0.794 and 0.816, whereas the AUC of the survival ROC was 0.798 and 0.846. Conclusion The results of this study could be used in clinical practice to support risk stratification. Trial registration This study was registered at ClinicalTrials.gov as NCT03593928. Supplementary Information The online version contains supplementary material available at 10.1186/s12959-021-00329-z.
关键词：Optical coherence tomography; Residual syntax score; Thin-cap fibroatheroma; Prognosis value