文章基本信息

标题：Two-port network modeling for bio-heat transfers in lungs
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作者：Jean-François Duhé ; Stéphane Victor ; Pierre Melchior 等
期刊名称：IFAC PapersOnLine
印刷版ISSN：2405-8963
出版年度：2021
卷号：54
期号：15
页码：169-174
DOI：10.1016/j.ifacol.2021.10.250
语种：English
出版社：Elsevier
摘要：AbstractIn open-heart surgery, temperature changes may severely damage organ tissues, therefore a better knowledge of thermal transient effects is required to improve temperature control. Heat transfer in a biological context is usually treated by means of empirical relationships or simple resistance models. In some cases, fairly simplified models only involving thermal resistanceRand a heat capacityCare used. More advanced models which may be accurate enough tend to rely on heavy finite element computations. An intermediate model is sought to more accurately describe transient effects. By combining the well-known Pennes’ bio-heat equation combined to a thermal two-port network, a circuit model is proposed to take into account thermal transients in a perfused tissue. A larger frequency band can be taken into account for such an approach. The proposed models may also consider the effect of blood perfusion on the temperature transients, as well as blood temperature fluctuations (as in extracorporeal circulation, for example) and metabolic heat generation. For a simple 1D scenario, sensitivities to different heat or temperature inputs are compared. The obtained impedance expressions are also analyzed for different branch levels of the lung.
关键词：KeywordsHeat equationbio-heat equationPennes equationblood perfusiontwo-port networkfractional calculusfractional systemfractional order model