文章基本信息

标题：Closed-loop control of anesthesia and hemodynamic system: a Model Predictive Control approach
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作者：Anca Maxim ; Dana Copot
期刊名称：IFAC PapersOnLine
印刷版ISSN：2405-8963
出版年度：2021
卷号：54
期号：15
页码：37-42
DOI：10.1016/j.ifacol.2021.10.228
语种：English
出版社：Elsevier
摘要：AbstractThis paper proposes a Model Predictive Control (MPC) approach of both anesthesia and hemodynamic systems. The designed control strategy has been validated on a novel and unique patient simulator. The aim of this paper is to evaluate the feasibility MIMO closed-loop control of anesthesia and hemodynamic variables taking into account the interaction (synergic and antagonistic) between subsystems. The proposed methodology takes into account patient variability, is robust to subsystems interaction and meets the clinical objectives. The algorithm is tested in simulation on a hypnosis-hemodynamic combined model for use during general anesthesia. The preliminary results are promising and show the effectiveness of the control procedure.
关键词：Keywordsanesthesiahemodynamic regulationclosed-loop control of anesthesiaModel Predictive Controloptimal drug dosing