文章基本信息

标题：Structural reduction of CRNs with linear sub-CRNs
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作者：Katalin M. Hangos ; György Lipták ; Gábor Szederkényi 等
期刊名称：IFAC PapersOnLine
印刷版ISSN：2405-8963
出版年度：2021
卷号：54
期号：14
页码：149-154
DOI：10.1016/j.ifacol.2021.10.344
语种：English
出版社：Elsevier
摘要：AbstractA novel systems theory-based structural reduction method is proposed in this paper that can be applied to chemical reaction networks (CRNs) including subsystems consisting of linear reactions, i.e. a linear sub-CRN. The reduced model is a delayed CRN with distributed delays having less complexes (monomials) and reactions than the original model. The reduction is based on the fact that the input/output response of a linear sub-CNR can be seen as a time-delayed input to output relationship, therefore linear sub-CNRs can be interpreted as reactions with distributed delay from their input to their output complexes. The practically important example of a kinetic model describing the spread of the COVID-19 epidemic is used as a case study to illustrate the basic concepts and the computation method.
关键词：KeywordsDelayModel reductionChemical Reaction NetworksCOVID