文章基本信息

标题：The effect of vitamin D deficiency state on oxidized low-density lipoprotein alteration in patients with type 2 diabetes
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作者：Salome Sadat Salehi ; Sahar Karimpour ; Soghra Rabizadeh 等
期刊名称：Functional Foods in Health and Disease
电子版ISSN：2160-3855
出版年度：2021
卷号：11
期号：8
页码：357-367
DOI：10.31989/ffhd.v11i8.815
语种：English
出版社：Food Science Publisher
摘要：The aim of this study was to compare oxidized low-density lipoprotein (oxLDL) and blood glucose in very low and low levels of vitamin D. Methods: A total of 25 type-2 diabetic patients with very low serum levels of 25-hydroxy vitamin D (severe deficiency –Results: Patients with severe vitamin D deficiency had higher FBS, PPG, HbA1C, and oxLDL than the vitamin D deficient group (P<0.05). We showed that the AUC of FBS, PPG, HbA1C, and oxLDL were in the range of 0.7-0.9, which indicates moderate accuracies in differentiating severe vitamin D deficiency from deficiency condition. Conclusion: In conclusion, diabetic patients with severe vitamin D deficiency had higher FBS, PPG, and oxLDL levels compared with deficient ones. ROC curve analysis of FBS, PPG, HbA1C, and oxLDL showed these markers are independent predictors of severe vitamin D deficiency and significantly discriminate between very low and low levels of vitamin D deficiency in patients with diabetes.
关键词：Type 2 diabetes mellitus;Vitamin D deficiency;OxLDL;Fasting blood glucose