文章基本信息

标题：Secondary analysis of malaria rapid diagnostic tests from rounds 5–8 of WHO product testing with a focus on false-negative results
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作者：Biao Xu ; Bo Tu ; Fang Chu 等
期刊名称：Military Medical Research
印刷版ISSN：2054-9369
出版年度：2021
卷号：8
DOI：10.1186/s40779-021-00345-0
语种：English
出版社：BioMed Central
摘要：Despite the widespread use of malaria rapid diagnostic test (RDT) in clinical practice, there are a lot of challenges. We conducted a secondary analysis of 129 malaria RDT data from rounds 5–8 of the World Health Organization (WHO) product testing summary and discuss the causes of false-negative (FN) results with a focus on low parasite density, improper RDT storage, operation and interpretation, and plasmodium falciparum with a pfhrp2/3 gene deletion. The results demonstrated that the malaria RDTs currently commercially available might cause FN results in practice. Supplementary Information The online version contains supplementary material available at 10.1186/s40779-021-00345-0.
关键词：Malaria; Rapid diagnostic tests; False-negative results; WHO product testing