文章基本信息

标题：The association between urinary bisphenol A levels and nonalcoholic fatty liver disease in Korean adults: Korean National Environmental Health Survey (KoNEHS) 2015-2017
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作者：Sang Joon An ; Eun-Jung Yang ; Subin Oh 等
期刊名称：Environmental Health and Preventive Medicine
印刷版ISSN：1342-078X
电子版ISSN：1347-4715
出版年度：2021
卷号：26
DOI：10.1186/s12199-021-01010-7
语种：English
出版社：Springer Japan
摘要：Nonalcoholic fatty liver disease (NAFLD) is becoming a global health problem. Bisphenol A (BPA), one of most widely used environmental chemicals, is suspected to be a contributor to the development NAFLD. This study was performed to examine the relationship between human BPA levels and risk of NAFLD. Methods The data ( n = 3476 adults: 1474 men and 2002 women) used in this study were obtained from the Korean National Environmental Health Survey III (2015-2017). BPA levels were measured in urine samples. NAFLD was defined using hepatic steatosis index after exclusion of other causes of hepatic diseases. Results There was a significant linear relationship between the elevated urinary BPA concentrations and risk of NAFLD. In a univariate analysis, odds ratio (OR) of the highest quartile of urinary BPA level was 1.47 [95% confidence interval (CI) 1.11-1.94
关键词：Bisphenol A; Hepatic steatosis index; Nonalcoholic fatty liver disease; Korean adults; Korean national environmental health survey