文章基本信息

标题：Persistence of virus-neutralizing antibodies in horses inoculated with two doses of a live equine herpesvirus type 1 vaccine with different vaccination intervals
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作者：Hiroshi BANNAI ; Yoshinori KAMBAYASHI ; Koji TSUJIMURA 等
期刊名称：Journal of Equine Science
印刷版ISSN：1340-3516
电子版ISSN：1347-7501
出版年度：2021
卷号：32
期号：3
页码：99-102
DOI：10.1294/jes.32.99
语种：English
出版社：Japanese Society of Equine Science
摘要：The antibody response in horses inoculated with 2 doses of a live equine herpesvirus type 1 vaccine with different vaccination intervals (1 to 3 months) was evaluated with regard to the persistence of virus-neutralizing (VN) antibodies. The durations for which the geometric mean VN titers were maintained significantly higher than those before the first vaccination (P<0.05) were up to 5 months in horses that received the vaccination with a 1-month interval (n=17) and 7 months for those that received it with a 2-month (n=17) or 3-month interval (n=14 or 17). The vaccination program with the 2-month interval was the most effective in maintaining VN antibodies for a long duration with the smallest gap of antibody decline between the first and second vaccinations.
关键词：enequine herpesvirus type-1;persistence;vaccination interval;virus-neutralizing antibody