文章基本信息

标题：Author Correction: Glucose and fatty acid metabolism involved in the protective effect of metformin against ulipristal-induced endometrial changes in rats
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作者：Marwa S. Hamza ; Eman Ramadan ; Salama A. Salama 等
期刊名称：Scientific Reports
电子版ISSN：2045-2322
出版年度：2021
卷号：11
DOI：10.1038/s41598-021-97931-y
语种：English
出版社：Springer Nature
摘要：Correction to: Scientific Reports 10.1038/s41598-021-88346-w, published online 23 April 2021 In the original version of the Article, Figure 4 was a duplication of Figure 3. The original Figure 4 and accompanying legend appear below. Figure 4 Effect of metformin or/and ulipristal on the expression of the proliferation markers of rats’ uteri. ( A– D) photomicrographs of uteri shows expression of PCNA ( A) Uterine wall in the control group. ( B) Uterine wall in ulipristal treated group. ( C) Uterine wall in metformin treated group. ( D) Uterine wall in the ulipristal and metformin treated group. × 400 magnification (scale bar = 20 μm). ( E) Expression quantification of the optical density reactivity of positive cells of PCNA by the ImageJ analysis system. ( F) Quantitative RT-PCR analysis of PCNA mRNA expression. ( G– J) Photomicrographs of uteri shows expression of Cyclin-D. ( G) Uterine wall in the control group. ( H) Uterine wall in ulipristal treated group. (I) Uterine wall in metformin treated group. ( J) Uterine wall in the ulipristal and metformin treated group. × 400 magnification (scale bar = 20 μm). ( K) Expression quantification of the optical density reactivity of positive cells by the ImageJ analysis system. ( L) Quantitative RT-PCR analysis of Cyclin D1 mRNA expression, Black arrow refers to reactivity in endometrial glands, red arrows refers to reactivity in stromal cells. Data in figures ( E) and ( K) is represented by mean ± SD (n = 7). All value of RT-PCR is expressed as the change in cycle threshold (ΔCt). Each dot represents mean of each group (n = 7, triplicate for each rat). Negative control (DEPC-treated water) showed no detectable fluorescent signals. a or b, Statistically significant from the control or ulipristal and metformin treated group respectively at P < 0.05 using one-way ANOVA followed by Tukey as a post hoc test. UPA ulipristal, MET metformin, UPA + MET co-treatment with ulipristal and metformin. The original Article has been corrected.