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标题：Author Correction: Elevated dimethylarginine, ATP, cytokines, metabolic remodeling involving tryptophan metabolism and potential microglial inflammation characterize primary open angle glaucoma
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作者：Sujith Kumar Pulukool ; Sai Krishna Srimadh Bhagavatham ; Vishnu Kannan 等
期刊名称：Scientific Reports
电子版ISSN：2045-2322
出版年度：2021
卷号：11
DOI：10.1038/s41598-021-97509-8
语种：English
出版社：Springer Nature
摘要：Correction to: Scientific Reports 10.1038/s41598-021-89137-z, published online 07 May 2021 The original version of this Article contained errors. There is a repeated error in the Results section under the subheading ‘Inhibition of NOS with DMAG invoked purinergic signaling and expression of cytokines in N9 microglia’, in the Methods section under the subheading ‘Quantitative PCR’, in Panel (i) of Figure 3, in the legend of Figure 3, and in Supplementary Table S5, where “P2Y 11” now reads: “P2Y 14” The original Figure 3 and accompanying legend appear below. Figure 3 Showing expression of P2 receptors in N9 microglial cells and DMAG induced ATP secretion and expression of cytokines as well as effect of NEM and sodium nitroprusside (SNP) showing ( a– i) N9 cells treated with DMAG inducing the expression of P2X receptors and P2Y receptors ( a) P2X 1 ( b) P2X 2 ( c) P2X 4 ( d) P2X 5 ( e) P2X 7 ( f) P2Y 6 ( g) P2Y 2 ( h) P2Y 4 ( i) P2Y 11. Showing N9 cells treated with DMAG (1 mM) with or without pre-incubation with NEM (1 μM) ( j) Secretion of ATP and inhibited by NEM. Showing upregulation of cytokines and inhibition by NEM ( k) TGFβ ( l) TNFα ( m) IFNɣ. Showing N9 cells treated with DMAG (1 mM) with or without pre-incubation with SNP (0.5 mM and 1 mM) ( n) secretion of ATP and its inhibition by SNP. Showing upregulation of cytokines and inhibition by SNP ( o) TNFα ( p) IFNy. The significance was calculated using Student T-test. * for P < 0.05, ** for P < 0.01, and *** for P < 0.001. For n numbers and the results provided as mean ± SEM, refer to text. Additionally, in Supplementary Table S5, the Accession number for Gene “IDO-1” was incorrectly given as “NM_001293690.1”. The correct Accession number is “NM_008324.2”. Furthermore, the primer sequences provided for Genes “IDO-1”, “IDO-2” and “TDO2” were incorrectly given as the human sequence instead of the mice sequence. The original Supplementary Table S5 file is provided below. The original Article and accompanying Supplementary Information file have been corrected. Supplementary Information Supplementary Information.