文章基本信息

标题：Lab-on-Paper Devices for Diagnosis of Human Diseases Using Urine Samples—A Review
本地全文：下载
作者：Wei-Chun Tai ; Yu-Chi Chang ; Dean Chou 等
期刊名称：Biosensors
电子版ISSN：2079-6374
出版年度：2021
卷号：11
期号：8
DOI：10.3390/bios11080260
语种：English
出版社：MDPI Publishing
摘要：In recent years, microfluidic lab-on-paper devices have emerged as a rapid and low-cost alternative to traditional laboratory tests. Additionally, they were widely considered as a promising solution for point-of-care testing (POCT) at home or regions that lack medical infrastructure and resources. This review describes important advances in microfluidic lab-on-paper diagnostics for human health monitoring and disease diagnosis over the past five years. The review commenced by explaining the choice of paper, fabrication methods, and detection techniques to realize microfluidic lab-on-paper devices. Then, the sample pretreatment procedure used to improve the detection performance of lab-on-paper devices was introduced. Furthermore, an in-depth review of lab-on-paper devices for disease measurement based on an analysis of urine samples was presented. The review concludes with the potential challenges that the future development of commercial microfluidic lab-on-paper platforms for human disease detection would face.
关键词：enmicrofluidic;paper-based devices;lab-on-paper;urine;non-invasive samples