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标题：Short-term PM _2.5 and cardiovascular admissions in NY State: assessing sensitivity to exposure model choice
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作者：Mike Z. He ; Vivian Do ; Siliang Liu 等
期刊名称：Environmental Health - a Global Access Science Source
印刷版ISSN：1476-069X
电子版ISSN：1476-069X
出版年度：2021
卷号：20
DOI：10.1186/s12940-021-00782-3
语种：English
出版社：BioMed Central
摘要：Air pollution health studies have been increasingly using prediction models for exposure assessment even in areas without monitoring stations. To date, most studies have assumed that a single exposure model is correct, but estimated effects may be sensitive to the choice of exposure model. Methods We obtained county-level daily cardiovascular (CVD) admissions from the New York (NY) Statewide Planning and Resources Cooperative System (SPARCS) and four sets of fine particulate matter (PM 2.5) spatio-temporal predictions (2002–2012). We employed overdispersed Poisson models to investigate the relationship between daily PM 2.5 and CVD, adjusting for potential confounders, separately for each state-wide PM 2.5 dataset. Results For all PM 2.5 datasets, we observed positive associations between PM 2.5 and CVD. Across the modeled exposure estimates, effect estimates ranged from 0.23% (95%CI: -0.06, 0.53%) to 0.88% (95%CI: 0.68, 1.08%) per 10 µg/m 3 increase in daily PM 2.5. We observed the highest estimates using monitored concentrations 0.96% (95%CI: 0.62, 1.30%) for the subset of counties where these data were available. Conclusions Effect estimates varied by a factor of almost four across methods to model exposures, likely due to varying degrees of exposure measurement error. Nonetheless, we observed a consistently harmful association between PM 2.5 and CVD admissions, regardless of model choice. Supplementary Information The online version contains supplementary material available at 10.1186/s12940-021-00782-3.
关键词：Particulate matter; Exposure assessment; Cardiovascular morbidity