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标题：The effect of acute aerobic exercise on central arterial stiffness, wave reflections, and hemodynamics in adults with diabetes: A randomized cross-over design
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作者：Kimberley L. Way ; Angela S. Lee ; Stephen M. Twigg 等
期刊名称：Journal of Sport and Health Science
印刷版ISSN：2095-2546
出版年度：2021
卷号：10
期号：4
页码：499-506
DOI：10.1016/j.jshs.2020.02.009
语种：English
出版社：Elsevier
摘要：Highlights • This is the first study examining the effect of acute aerobic exercise on central arterial stiffness, wave reflections, and hemodynamics in people with diabetes. • A significant group × time interaction was found for changes in central systolic blood pressure and augmentation index at a heart rate of 75 bpm. • A reduction in central systolic blood pressure was observed following high-intensity interval exercise; no changes were found after moderate-intensity continuous exercise or control. • A reduction in augementation index at a heart rate of 75 bpm was observed following both types of aerobic exercise, but not control. • This provides valuable insight into possible benefits with aerobic exercise and vascular health in diabetes. Background Individuals with diabetes have greater central arterial stiffness, wave reflections, and hemodynamics, all of which promote the accelerated cardiovascular pathology seen in this population. Acute aerobic exercise has been shown to be an effective strategy for reducing central arterial stiffness, wave reflections, and hemodynamics in healthy individuals; however, the effects of acute aerobic exercise in reducing these outcomes is not well established in people with diabetes. Recently, implementation of high-intensity interval exercise (HIIE) has shown superior improvements in cardiovascular health outcomes when compared to traditional aerobic exercise. Yet, the effect of HIIE on the aforementioned outcomes in people with diabetes is not known. The purpose of this study was to (i) describe the central arterial stiffness, wave reflections, and hemodynamic responses to a bout of HIIE and moderate-intensity continuous exercise (MICE) in adults with diabetes; and (ii) compare the effects of HIIE and MICE on the aforementioned outcomes. Methods A total of 24 adult men and women (aged 29–59 years old) with type 1 ( n = 12) and type 2 ( n = 12) diabetes participated in a randomized cross-over study. All participants completed the following protocols: (i) HIIE: cycling for 4 × 4 min at 85%–95% of heart rate peak (HR peak), interspersed with 3 min of active recovery at 60%–70%HR peak; (ii) MICE: 33 min of continuous cycling at 60%–70%HR peak; and (iii) control (CON): lying quietly in a supine position for 30 min. Results A significant group × time effect was found for changes in central systolic blood pressure ( F = 3.20, p = 0.01) with a transient reduction for the HIIE group but not for the MICE or CON groups. There was a significant group × time effect for changes in augmentation index at a heart rate of 75 beats/min ( F = 2.32, p = 0.04) with a decrease following for HIIE and MICE but not for CON. For all other measures of central arterial stiffness and hemodynamics, no significant changes were observed ( p > 0.05). Conclusion A bout of HIIE appears to lead to a greater transient reduction in central systolic blood pressure than the reduction observed following MICE; however, both HIIE and MICE improved augmentation index at a heart rate of 75 beats/min in people with diabetes. There was no significant difference in response to HIIE and MICE in all outcomes. This provides preliminary evidence on the role of HIIE on such outcomes in people with diabetes.
关键词：Augmentation index;Central systolic blood pressure;Diabetes;High-intensity interval exercise