文章基本信息

标题：DYS533のピークが低い試料において観察されたフランキング領域の一塩基置換
本地全文：下载
作者：綿引晴彦 ; 藤井宏治 ; 深川貴志等
期刊名称：日本法科学技術学会誌
印刷版ISSN：1880-1323
电子版ISSN：1881-4689
出版年度：2021
卷号：26
期号：2
页码：225-229
DOI：10.3408/jafst.798
语种：Japanese
出版社：Japanese Association of Forensic Science and Technology
摘要：We previously typed Y-STRs of 1299 Japanese samples using the Yfiler Plus kit and found three cases with a low peak of DYS533. In this study, we sequenced the flanking regions of DYS533 in these three samples and found a single nucleotide substitution at the position 111 bp upstream from the DYS533 repeat region. Because our previous study revealed that the Y-chromosomes of these three samples belong to haplogroup D-M57*, the mutation of the single nucleotide is likely to have occurred on the common ancestral Y-chromosome of these samples. The single nucleotide substitution may have caused the low peak of DYS533 in the three samples.
关键词：Forensic DNA typing;STR;Yfiler Plus;DYS533;Single nucleotide substitution