摘要:The presence of rich phytochemicals inCarica papayalinn. leaves are potentially beneficial in pharmaceutical, nutraceutical and food industries. This work aims to investigate the roles of solvent flowrate for the predictive behaviour of supercritical fluid extraction of essential oil-rich extracts by broken-intact-cell modelling approach. Through kinetic model fitting of experimental data, the adjustable parameters namelyG,φk,ZandYwere determined through error minimization procedure. From the cumulative extraction curve at solvent rate from 4 – 8 mL/min, the values of mass transfer coefficients were in the range of 4.40 × 10−5m2/s – 19.92 × 10−5m2/s with an overall relative 8.67% AARD. The grinding index and end of fast extraction time period was within the range of 0.144 – 0.258 and 30.38 – 91.17 min respectively. The role of solvent flowrate played an influential role in the extraction of papaya leaves extract.