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  • 标题:A Tractable Logic for Molecular Biology
  • 本地全文:下载
  • 作者:Adrien Husson ; Jean Krivine
  • 期刊名称:Electronic Proceedings in Theoretical Computer Science
  • 电子版ISSN:2075-2180
  • 出版年度:2019
  • 卷号:306
  • 页码:101-113
  • DOI:10.4204/EPTCS.306.17
  • 语种:English
  • 出版社:Open Publishing Association
  • 摘要:We introduce a logic for knowledge representation and reasoning on protein-protein interactions. Modulo a theory, formulas describe protein structures and dynamic changes. They can be composed in order to add or remove static and dynamic observations. A second-order circumscription operator then enables nonmonotonic reasoning on the changes implied by a formula. We introduce deduction rules that produce formulas which are, up to equivalence, in a first-order fragment with decidable satisfiability and validity. Importantly, the rules can produce circumscribed formulas.
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