文章基本信息

标题：The Post-COVID-19 Era: Interdisciplinary Demands of Contagion Surveillance Mass Spectrometry for Future Pandemics
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作者：Chaitanya Giri ; Henderson James Cleaves ; Markus Meringer 等
期刊名称：Sustainability
印刷版ISSN：2071-1050
出版年度：2021
卷号：13
期号：14
页码：7614
DOI：10.3390/su13147614
语种：English
出版社：MDPI, Open Access Journal
摘要：Mass spectrometry (MS) can become a potentially useful instrument type for aerosol, droplet and fomite (ADF) contagion surveillance in pandemic outbreaks, such as the ongoing SARS-CoV-2 pandemic. However, this will require development of detection protocols and purposing of instrumentation for in situ environmental contagion surveillance. These approaches include: (1) enhancing biomarker detection by pattern recognition and machine learning; (2) the need for investigating viral degradation induced by environmental factors; (3) representing viral molecular data with multidimensional data transforms, such as van Krevelen diagrams, that can be repurposed to detect viable viruses in environmental samples; and (4) absorbing engineering attributes for developing contagion surveillance MS from those used for astrobiology and chemical, biological, radiological, nuclear (CBRN) monitoring applications. Widespread deployment of such an MS-based contagion surveillance could help identify hot zones, create containment perimeters around them and assist in preventing the endemic-to-pandemic progression of contagious diseases.