文章基本信息

标题：Graphene nanoplatelet and graphene oxide functionalization of face mask materials inhibits infectivity of trapped SARS-CoV-2
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作者：Flavio De Maio ; Valentina Palmieri ; Gabriele Babini 等
期刊名称：iScience
印刷版ISSN：2589-0042
出版年度：2021
卷号：24
期号：7
页码：1-15
DOI：10.1016/j.isci.2021.102788
语种：English
出版社：Elsevier
摘要：SummaryRecent advancements in bidimensional nanoparticles production such as graphene (G) and graphene oxide (GO) have the potential to meet the need for highly functional personal protective equipment (PPE) against SARS-CoV-2 infection. The ability of G and GO to interact with microorganisms provides an opportunity to develop engineered textiles for use in PPE and limit the spread of COVID-19. PPE in current use in high-risk settings for COVID transmission provides only a physical barrier that decreases infection likelihood and does not inactivate the virus. Here, we show that virus pre-incubation with soluble GO inhibits SARS-CoV-2 infection of VERO cells. Furthermore, when G/GO-functionalized polyurethane or cotton was in contact SARS-CoV-2, the infectivity of the fabric was nearly completely inhibited. The findings presented here constitute an important innovative nanomaterial-based strategy to significantly increase PPE efficacy in protection against the SARS-CoV-2 virus that may implement water filtration, air purification, and diagnostics methods.Graphical abstractDisplay OmittedHighlights•Graphene oxide (GO) traps Sars-CoV-2 particles in liquid medium•Cotton or polyurethane can be functionalized with graphene or GO nanoparticles•Infection is inhibited when Sars-CoV-2 contacts with functionalized fabrics•Graphene-functionalized fabrics are effective against bacteria and are biocompatibleHealth sciences; Public health; Disease; Materials science; Nanostructure