摘要:CHRONIC KIDNEY DISEASE (CKD) IS A PATHOLOGY THAT CAN LEAD TO SLOW LOSS OF NEPHRONS AND RENAL FUNCTION, WITH THE ONSET OF TERMINAL CKD.THE PATHOPHYSIOLOGICAL CHANGES ARE COMPLEX, AND THE ASSOCIATION, ADVERSE, WITH A LARGE CARDIO-VASCULAR PATHOLOGY, CAN LEAD TO THE DEVELOPMENT OF SEPSIS LATER WITH THE RAPID DECLINE OF RENAL FUNCTION.THE CASE OF A MALE PATIENT WITH KNOWN CARDIAC PATHOLOGY, RECENTLY DISCHARGED FROM THE CARDIOLOGY CLINIC, WHO PRESENTS AT THE ER (EMERGENCY ROOM), WITH A VERY SERIOUS GENERAL CONDITION, WITH RESPIRATORY PATHOLOGY, DYSPNEA WITH ORTHOPNEA, OEDEMA OF THE LOWER LIMBS, PALE TEGUMENTS, SWEAT, BILATERAL SUCCESSIVE RALES, REASONS FOR BEING ADMITTED TO THE CARDIOLOGY SECTION, FALL INTO THIS CATEGORY.AFTER MULTIPLE CLINIC-PARACLINICAL INVESTIGATIONS WERE PERFORMED IN THE CLINIC, THE GENERAL CONDITION OF THE PATIENT WORSENED AFTER APPROXIMATELY 10 DAYS, WHICH IS WHY HE IS TRANSFERRED TO THE INTENSIVE CARE CLINIC, WHERE FURTHER INVESTIGATIONS ARE CARRIED OUT, TREATING THE FACTORS THAT HAVE WORSENED THE PATIENT'S CONDITION, INCLUDING TREATMENT OF ACUTE CKD AND CARRYING OUT THERAPY FOR RENAL FUNCTION REPLACEMENT BY HEMODIALYSIS (HD).HEMODIALYSIS WAS A USEFUL AND LIFE-SAVING THERAPEUTIC MEASURE, CHRONIC KIDNEY DISEASE, ASSOCIATED WITH A SERIOUS CARDIAC PATHOLOGY, FAVOURING THE ONSET OF SEPSIS.