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  • 标题:VITAMIN D AND ITS RELATIONSHIP WITH CARDIOVASCULAR DISEASES
  • 本地全文:下载
  • 作者:Ana Maria Alexandra STANESCU ; Ioana Veronica GRAJDEANU ; Ovidiu Gabriel BRATU
  • 期刊名称:Research and Science Today
  • 印刷版ISSN:2247-4455
  • 电子版ISSN:2285-9632
  • 出版年度:2020
  • 期号:19
  • 页码:191-199
  • 语种:English
  • 出版社:RST Journal
  • 摘要:VITAMIN D DEFICIENCY HAS BEEN ASSOCIATED WITH DISEASES SUCH AS RICKETS, OSTEOMALACIA, OSTEOPOROSIS, SKIN DISEASES AND CARDIOVASCULAR DISEASE.VITAMIN D DEFICIENCY IS ASSOCIATED WITH INCREASED INFLAMMATION, INCREASED EXPRESSION OF INFLAMMATORY CYTOKINES, ENDOTHELIAL CELLS AND DYSFUNCTION OF VASCULAR SMOOTH MUSCLE CELLS AND DECREASED VDR EXPRESSION AND ACTIVITY, WHICH MAY LEAD TO THE DEVELOPMENT OF VASCULAR DISEASES, SUCH AS ATHEROSCLEROSIS, ANEURYSMS, VASCULAR CALCIFICATIONS, AND ARTERIAL HYPERTENSION.ALTHOUGH THERE IS EVIDENCE THAT VITAMIN D DEFICIENCY IS ASSOCIATED WITH CARDIOVASCULAR DISEASE, A CAUSAL RELATIONSHIP HAS NOT BEEN IDENTIFIED YET.
  • 关键词:VITAMIN D DEFICIENCY;ATHEROSCLEROSIS;CARDIOVASCULAR DISEASE.
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