文章基本信息

标题：Non-communicable diseases – a catastrophe for South Africa
本地全文：下载
作者：Ebrahim Samodien ; Yoonus Abrahams ; Christo Muller 等
期刊名称：South African Journal of Science
印刷版ISSN：0038-2353
电子版ISSN：1996-7489
出版年度：2021
卷号：117
期号：5-6
页码：1-6
DOI：10.17159/sajs.2021/8638
语种：English
出版社：The Foundation for Research Development
摘要：Non-communicable diseases contribute significantly to the disease burden within South Africa.In the most unequal of societies in the world, poverty and socio-economic disparity are amongst the greatest obstacles facing South Africans, impacting heavily on health care.Adverse socio-environmental factors, especially those experienced during early life, can, through neurobiological and epigenetic mechanisms, developmentally programme the outcome of obesity, diabetes, cardiovascular disease and mental health disorders in adulthood.In this narrative review, we describe the social environment experienced by South Africans and discuss the potential contribution of epigenetics to the current and future prevalence of non-communicable diseases.A large part of the population (including 60% of young children) lives in poverty and endures challenging socio-economic environments, due to high unemployment, alcohol and substance abuse, and inter-partner violence.It is imperative that socio-economic factors be considered as risk factors for strategies aimed at reducing or preventing these disorders.If the current situation is left unchecked, the disease incidences could be exacerbated, and be potentially catastrophic for future generations.The consequences can be widespread and can have a direct effect on the future health and economic development of the country.Thus, child and adolescent health requires urgent attention and should be placed at the centre of the healthcare system.Early interventions providing optimum nutrition, a secure environment, together with physical activity and education should be the cornerstones for creating a healthier population for the future.
关键词：biology of misfortune;child health;epigenetics;chronic illness;nutrition;social inequality