文章基本信息

标题：Review the Regulation of Plasma Membrane Calcium Channel in Cancer and Patch Clamp Technique
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作者：Nanjun Chen ; Qigeng Fang
期刊名称：E3S Web of Conferences
印刷版ISSN：2267-1242
电子版ISSN：2267-1242
出版年度：2021
卷号：271
页码：1-9
DOI：10.1051/e3sconf/202127104037
语种：English
出版社：EDP Sciences
摘要：As one of the most versatile and universal second messengers, calcium plays an essential role in cell life. Here we briefly reviewed the research progress of how different calcium channels are located at the cell plasma membrane, including voltage-gated calcium channels (VGCCs), receptor-operated channels (ROC), and store-operated channels (ROC). These channels can regulate different cancer progression. Afterward, the patch clamp technique's development and operating principle, an important quantitative method used for ion channel investigation, are introduced in this paper.