文章基本信息

标题：Effect of water temperature and microcystins on the pharmacokinetics of epigallocatechin gallate (EGCG) in snakehead fish ( Ophiocephalus argus Cantor)
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作者：Xiao-Chen Dong ; Lu-Ting Ye ; Jin Zhao 等
期刊名称：E3S Web of Conferences
印刷版ISSN：2267-1242
电子版ISSN：2267-1242
出版年度：2021
卷号：261
页码：1-4
DOI：10.1051/e3sconf/202126102028
语种：English
出版社：EDP Sciences
摘要：The study was conducted to evaluate the effect of water temperatures and intraperitoneal administration of microcystins (MCs) on the pharmacokinetics characteristics of epigallocatechin gallate (EGCG) in snakehead fish (Ophiocephalus argus Cantor) by RP-HPLC method. The results showed that EGCG was absorbed and eliminated more faster at 20ºC than at 10ºC. Then the detected results also showed that EGCG was significantly absorbed fast in MCs-treated group than in control group. However, EGCG elimination became very lowly in MCs-treated group. Therefore, the pharmacokinetic characteristics of EGCG were significantly affected by water temperature and MCs toxin.