文章基本信息

标题：Autophagy in Lepidoptera: more than old wine in new bottle
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作者：G Tettamanti ; Y Cao ; Q Feng 等
期刊名称：Invertebrate Survival Journal
电子版ISSN：1824-307X
出版年度：2011
卷号：8
期号：1
页码：5-14
语种：English
出版社：Universita degli Studi di Modena e Reggio Emilia
摘要：Autophagy is a cellular pathway that leads to the degradation of proteins and organelles. Thisprocess is usually involved in the maintenance of cell homeostasis when the organism experiences nutrient starvation, but in holometabolous insects autophagy also intervenes in the demolition of larval tissues and organs during metamorphosis. This review summarizes the current knowledge about autophagy research in Lepidoptera and discusses the use of moths and butterflies as models for studying the roles and regulation of autophagy. It also gives insights into the cooperation between autophagy and apoptosis in cell death events that occur in lepidopteran in vivo and in vitro systems.
关键词：autophagy;Lepidoptera;Bombyx mori;ATG genes;apoptosis