文章基本信息

标题：Understanding and perceptions of final-year Doctor of Pharmacy students about generic medicines in Karachi, Pakistan: a quantitative insight
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作者：Shazia Qasim Jamshed ; Mohamad Izham Mohamad Ibrahim ; Mohamad Azmi Hassali 等
期刊名称：Advances in Medical Education and Practice
电子版ISSN：1179-7258
出版年度：2015
卷号：6
页码：359-366
DOI：10.2147/AMEP.S27762
出版社：Dove Medical Press Ltd
摘要：General objective: To evaluate the understanding and perceptions of generic medicines among final-year Doctor of Pharmacy students in Karachi, Pakistan. Methods: A 23-item survey instrument that included a question on the bioequivalence limits and Likert-type scale questions regarding the understanding and perceptions of generic medicines among the students was executed. Cronbach’s alpha was found to be 0.62. Results: Responses were obtained from 236 final-year Doctor of Pharmacy students (n=85 from a publicly funded institute; n=151 from a privately funded institute). When comparing a brand-name medicine to a generic medicine, pharmacy students scored poorly on bioequivalence limits. More than 80% of the students incorrectly answered that all the products that are rated as generic equivalents are therapeutically equivalent to each other ( P <0.04). Half of the students agreed that a generic medicine is bioequivalent to the brand-name medicine ( P <0.001). With regard to quality, effectiveness, and safety, more than 75% of the students disagreed that generic medicines are of inferior quality and are less effective than brand-name medicines ( P <0.001). More than 50% of the students disagreed that generic medicines produce more side effects than brand-name medicines ( P <0.001). Conclusion: The current study identified a positive perception toward generic medicines but also gaps in the understanding of generic medicines. Pharmacy students lacked a thorough understanding of the concepts of bioequivalence. Pharmacy academia should address these issues, which will help build confidence in generic medicines and increase the generic medicine use in Pakistan.
关键词：safety; curriculum; efficacy