文章基本信息

标题：New flavane gallates from the aerial part of an African/Arabian medicinal plant Plicosepalus curviflorus by LC-MS and NMR based molecular characterization
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作者：Areej Mohammad Al-Taweel ; Shagufta Perveen ; Saleh Ibrahim Alqasoumi 等
期刊名称：Journal of King Saud University - Science
印刷版ISSN：1018-3647
出版年度：2021
卷号：33
期号：2
页码：1-9
DOI：10.1016/j.jksus.2020.101289
语种：English
出版社：Elsevier
摘要：Graphical abstractDisplay OmittedAbstractPlicosepalus curviflorusis distributed in Africa, Yemen and Saudi Arabia and applied to treat cancer, tonsillitis, otitis media and for curing diabetes. The objective of this study is to isolate chemical constituents from this medicinally important plant and it yielded one undescribed gallocatechin derivative1along with nine known compounds2–10. In this study, the metabolite profiling ofn-butanol fraction ofP. curvifloruswas also measured by using liquid chromatography-quadrupole time-of-flight mass spectrometry (LC-QTOf-MS). Our research provided the facts for the theory that this plant is a good source of flavane and flavonoids and can be used as medicine. This application allowed to unambiguously identify eight compounds11–18fromn-butanol soluble fraction ofP. curviflorus. We describe here complete characterization of one new compound isolated from then-butanol soluble fraction ofP. curviflorusby NMR and ESI-MS. To the best of our good grasp, compounds12–15, represents the example of substituted catechin derivatives identified by LC-QTOf-MS method.
关键词：Plicosepalus curviflorus;Flavane gallates;Catechin derivatives