文章基本信息

标题：The genome sequence of Aloe vera reveals adaptive evolution of drought tolerance mechanisms
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作者：Shubham K. Jaiswal ; Shruti Mahajan ; Abhisek Chakraborty 等
期刊名称：iScience
印刷版ISSN：2589-0042
出版年度：2021
卷号：24
期号：2
页码：1-47
DOI：10.1016/j.isci.2021.102079
语种：English
出版社：Elsevier
摘要：SummaryAloe verais a species from Asphodelaceae family having characteristics like drought resistance and numerous medicinal properties. However, the genetic basis of these phenotypes is yet unknown primarily due to unavailability of its genome sequence. Thus, we report the firstAloe veragenome sequence comprising of 12.93 Gbp and harboring 86,177 protein-coding genes. It is the first genome from Asphodelaceae family and the largest angiosperm genome sequenced and assembled till date. We also report the first genome-wide phylogeny of monocots includingAloe verato resolve its phylogenetic position. The comprehensive comparative analysis ofAloe verawith other available high-quality monocot genomes revealed adaptive evolution in several genes of drought stress response, CAM pathway, and circadian rhythm and positive selection in DNA damage response genes inAloe vera. This study provides clues on the genetic basis of evolution of drought stress tolerance capabilities ofAloe vera.Graphical abstractDisplay OmittedHighlights•FirstAloe veragenome of 12.93 Gbp harboring 86,177 protein-coding genes•First genome from Asphodelaceae family and phylogeny of monocots withAloe vera•Adaptive evolution in drought stress response, CAM pathway, circadian rhythm genes•Clues on the genetic basis of evolution of drought stress tolerance capabilitiesBiological Sciences; Genetics; Phylogenetics; Evolutionary Biology