文章基本信息

标题：Protocol for synthesis of di- and tri-substituted s-triazine derivatives
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作者：Ayman El-Faham ; Anamika Sharma ; Muhammad Farooq 等
期刊名称：MethodsX
印刷版ISSN：2215-0161
电子版ISSN：2215-0161
出版年度：2020
卷号：7
页码：1-5
DOI：10.1016/j.mex.2020.100825
语种：English
出版社：Elsevier
摘要：AbstractThe present protocol describes the synthesis of di and tri-substituted s-triazine derivatives•s-Triazine undergoes sequential nucleophilic substitution reaction but order of nucleophile is very crucial.•It is very difficult to substitute any nucleophile except amine once amine is incorporated onto s-triazine.•During the synthesis ofO,N-type substituted s-triazine, always O-type should be incorporated first.Graphical abstractDisplay Omitted
关键词：Orthogonal chemoselectivity;Cyanuric chloride;Nucleophilic substitution;Amines;Alcohol