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标题：Microelectrodes from PEDOT-carbon nanofiber composite for high performance neural recording, stimulation and neurochemical sensing
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作者：Valentin Saunier ; Emmanuel Flahaut ; Marie-Charline Blatché 等
期刊名称：MethodsX
印刷版ISSN：2215-0161
电子版ISSN：2215-0161
出版年度：2020
卷号：7
页码：1-10
DOI：10.1016/j.mex.2020.101106
语种：English
出版社：Elsevier
摘要：AbstractThis present method describes a versatile approach for the electrochemical synthesis of a composite material of Poly (3,4-ethylenedioxythiophene) (PEDOT) and Carbon Nanofibers (CNFs) for neural interfaces and biosensing applications. Oxidized CNFs were utilized as dopants of PEDOT to prepare the composite coating through electrochemical deposition on microelectrodes arrays (MEA). The experimental results of this study showed that PEDOT:CNF microelectrodes exhibit remarkable electrochemical properties, combining low impedance, high surface area, high charge injection capability and reliable neurotransmitters monitoring using amperometric techniques. Taken together, these results suggest the great potential of PEDOT:CNF composite for developing next-generation multifunctional microelectrodes for applications in neural therapies.•A simple approach for the electrochemical synthesis of PEDOT:CNF composite material on microelectrodes for neural interfaces and neurochemical sensing.•PEDOT:CNF microelectrodes exhibit remarkable electrochemical properties, combining low impedance and high charge injection capabilities.•PEDOT:CNF microelectrodes allowed the reliable detection of neurotransmitters with improved sensitivity.Graphical abstractDisplay Omitted
关键词：PEDOT:CNF;Carbon nanofibers;Microelectrodes;Neural interfaces;Electrical stimulation;Electrochemical sensing