摘要:The present study was conducted to evaluate the synthesis of lactulose from whey lactose by using 1, 2 and 3M sodium aluminates as alkaline catalyst in batch reaction system at 30 and 70°C. The effect of different sodium aluminates molarities on the isomerization of lactose to lactulose and the time periods were also investigated. The maximum conversion of lactose to lactulose and the by-products formation have been investigated. The HPLC technique was used to determine whey lactulose, B vitamins and the by-products formation. After 1 h at 70°C, by using 3M of sodium aluminates, the isomerization yield was more than 66%. The present study describes an appropriate method for obtaining sweet whey with acceptable yields of lactulose.