摘要:Background: Preprint usage is growing rapidly in the life sciences; however, questions remain on the relativequality of preprints when compared to published articles. An objective dimension of quality that is readilymeasurable is completeness of reporting, as transparency can improve the reader’s ability to independentlyinterpret data and reproduce findings.Methods: In this observational study, we initially compared independent samples of articles published in bioRxivand in PubMed-indexed journals in 2016 using a quality of reporting questionnaire. After that, we performed pairedcomparisons between preprints from bioRxiv to their own peer-reviewed versions in journals.Results: Peer-reviewed articles had, on average, higher quality of reporting than preprints, although the differencewas small, with absolute differences of 5.0% [95% CI 1.4, 8.6] and 4.7% [95% CI 2.4, 7.0] of reported items in theindependent samples and paired sample comparison, respectively. There were larger differences favoring peer-reviewed articles in subjective ratings of how clearly titles and abstracts presented the main findings and how easyit was to locate relevant reporting information. Changes in reporting from preprints to peer-reviewed versions didnot correlate with the impact factor of the publication venue or with the time lag from bioRxiv to journalpublication.Conclusions: Our results suggest that, on average, publication in a peer-reviewed journal is associated withimprovement in quality of reporting. They also show that quality of reporting in preprints in the life sciences iswithin a similar range as that of peer-reviewed articles, albeit slightly lower on average, supporting the idea thatpreprints should be considered valid scientific contributions.
关键词:Quality of reporting; Preprint; Peer review; Publication; bioRxiv; Scientific journal