摘要:Gambusia affinis is a fresh-water fish, but occurs also in brackish water. In aquatic resources, fishes are sensitive to the toxic substances mixed into water and deleterious effect of metals or heavy metals on fishes. The mosquitoes are breeding the larvae into the water which is the feeding source of the mosquito fish, called as Mosquito fish. The toxic substances are damage to the organism and degree of the cell damage reflects the various concentrations of the pollutants. In the present study an attempt is made to the Monocrotophos, an industrial as well agricultural effluence on Gambusia affinis. 50% mortality was exposure to Monocrotophos on 0.4 ppm at 96 hrs. The impact of Monocrotophos on the gill of Gambusia affinis, gill filaments are twisted and primary axis is in filtered of Gambusia affinis. The gill exhibited a film of coagulated mucous over the gill surface.