文章基本信息

标题：Role of Proteus mirabilis in Caffeine DegradationâA Preliminary Bioinformatics Study
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作者：Thangaraj Naina ; Siddharth Sharan ; Suneetha Vuppu 等
期刊名称：Research Journal of Recent Sciences
电子版ISSN：2277-2502
出版年度：2013
卷号：2
页码：33-40
语种：English
出版社：International Science Community Association
摘要：An attempt to find the role of Proteus mirabilis in caffeine degradation using bioinformatics tools has been made here. Soils from coffee industries were taken and the bacterium was isolated and found to degrade caffeine. Identification of the bacterium through Sangers dideoxy sequencing of 16S rDNA was done and its genome taken from online database was used for homology modeling of the enzyme to identify regions of similarity and enzyme structure prediction. Also attempts to secondary structure prediction and protein threading has been done to study the enzyme and compare the enzymes of Proteus mirabilis with that of other reported caffeine degrading organisms.
关键词：Caffeine degradation;bioinformatics;homology modeling;protein threading;secondary structure prediction