文章基本信息

标题：The Role of Motor and Environmental Visual Rhythms in Structuring Auditory Cortical Excitability
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作者：Monica N. O'Connell ; Annamaria Barczak ; Tammy McGinnis 等
期刊名称：iScience
印刷版ISSN：2589-0042
出版年度：2020
卷号：23
期号：8
页码：1-27
DOI：10.1016/j.isci.2020.101374
语种：English
出版社：Elsevier
摘要：SummaryPrevious studies indicate that motor sampling patterns modulate neuronal excitability in sensory brain regions by entraining brain rhythms, a process termed motor-initiated entrainment. In addition, rhythms of the external environment are also capable of entraining brain rhythms. Our first goal was to investigate the properties of motor-initiated entrainment in the auditory system using a prominent visual motor sampling pattern in primates, saccades. Second, we wanted to determine whether/how motor-initiated entrainment interacts with visual environmental entrainment. We examined laminar profiles of neuronal ensemble activity in primary auditory cortex and found that whereas motor-initiated entrainment has a suppressive effect, visual environmental entrainment has an enhancive effect. We also found that these processes are temporally coupled, and their temporal relationship ensures that their effect on excitability is complementary rather than interfering. Altogether, our results demonstrate that motor and sensory systems continuously interact in orchestrating the brain's context for the optimal sampling of our multisensory environment.Graphical AbstractDisplay OmittedHighlights•Our study demonstrates that saccades modulate A1 excitability•Rhythmic visual stimuli entrain A1 neural oscillations to a high excitability phase•Saccades entrain A1 neural oscillations to an opposite, suppressive state•Saccade probability increases between visual stimuli likely to avoid interferenceBiological Sciences; Neuroscience; Sensory Neuroscience