文章基本信息

标题：Dynamics of the Generalized Tumor-Virotherapy Model with Time Delay Effect
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作者：Sarud Udomchalermpat ; Sanoe Koonpraseart ; Ekkachai Kunnawuttipreechachan 等
期刊名称：Engineering Letters
印刷版ISSN：1816-093X
电子版ISSN：1816-0948
出版年度：2020
卷号：28
期号：3
页码：887-897
语种：English
出版社：Newswood Ltd
摘要：In this work, we analyze dynamics of the general-ized tumor-virotherapy model. Firstly, we investigate equilibriaof the model and find stability conditions on the model’s param-eters for each equilibrium. We also determine the conditions forthe existence of a Hopf bifurcation, which shows the oscillatoryof the solutions. The behavior of the model is shown withwell-known biologically admissible growth functions, such aslogistic, Gompertz and von Bertalanffy functions. Finally, weillustrate various classes of numerical simulations to supportthe analytical results.
关键词：virotherapy; tumor; growth function; Hopf bifurcation.