文章基本信息

标题：Potential Beneficial Effects of Chenopodium quinoa and Salvia hispanica L. in Glucose Homeostasis in Hyperglycemic Mice Model
本地全文：下载
作者：Raquel Selma-Gracia ; Claudia Monika Haros ; José Moisés Laparra 等
期刊名称：Proceedings
电子版ISSN：2504-3900
出版年度：2020
卷号：54
期号：33
页码：2
DOI：10.3390/proceedings2020053002
语种：English
出版社：MDPI AG
摘要：Impaired glucose homeostasis is associated with an increased risk of developing metabolic alterations. In this study, a model in which mice treated with streptozotocin were fed a high-fat diet was used to mimic early stages of the onset of metabolic disorders, and different bread formulations were administrated to evaluate the effect of replacing wheat flour with Chenopodium quinoa (Q) (25%) and Salvia hispanica L. (Sh) (20%). Plasmatic glucose and insulin concentrations were quantified and the homeostasis model assessment (HOMAir) was calculated. Q and Sh showed a lower tendency to hyperglycemia compared to wheat bread (WB). Besides, these low glucose levels were accompanied by three-fold lower values of HOMAir respect to WB, suggesting an improved insulin sensitivity. Thus, inclusion of C. quinoa and S. hispanica into bread formulations could improve the control of glucose homeostasis, which could help to prevent/ameliorate metabolic glucose alterations.