文章基本信息

标题：Prospect of Plant-based Flavonoids to Overcome Antibacterial Resistance A Mini-Review
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作者：Abdi Wira SEPTAMA ; Nordin SIMBAK ; Eldiza Puji RAHMI 等
期刊名称：Walailak Journal of Science and Technology (WJST)
印刷版ISSN：2228-835X
出版年度：2020
卷号：17
期号：5
页码：503-513
语种：English
出版社：Institute of Research and Development, Walailak University.
摘要：Although antibiotic has been frequently used for the treatment of infection, it has led to the emergence of resistant problem. Plant-derived compounds are alternative source for discovering novel therapeutics. Flavonoid is widely distributed and present in plant kingdom. This compound possessed several pharmacological properties including antibacterial. This review aims to present some information about the potency of flavonoids as antibacterial compound including their mechanism of antibacterial action as well as the relationship between their activity and flavonoid structure. The synergistic effect of flavonoids when used in combination with antibiotics against resistant bacterial is also described. Published literatures were collected from data bases such as PubMed, Google Scholar, Science Direct and Scopus. Scientific papers were selected based on information of antibacterial activity of flavonoid compounds. The information may provide an insight on the potency of flavonoid compounds to overcome resistant problem.
关键词：Antibiotic;Antibacterial;Bacterial resistant;Flavonoid;Natural product;Synergistic