文章基本信息

标题：Antioxidant activity of flavonoid compounds isolated from the petals of Hibiscus rosa sinensis
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作者：Sumathy Rengarajan ; Vijayalakshmi Melanathuru ; Chandramohan Govindasamy 等
期刊名称：Journal of King Saud University - Science
印刷版ISSN：1018-3647
出版年度：2020
卷号：32
期号：3
页码：2236-2242
DOI：10.1016/j.jksus.2020.02.028
语种：English
出版社：Elsevier
摘要：AbstractHibiscus rosasinensis, medicinal plant known for its various medicinal properties. The present study was to identify and characterize the flavonoid compound from the petals ofHibiscus rosa sinensis. The antioxidant compounds were isolated by Silica Gel G Column chromatography. From the fractions, C5 shows the highest antioxidant activity compared to C3 & C4 compounds. DNA damage protection activity results indicated that two major bands super coiled DNA and open circular DNA was protected by the presence of different concentration (5 µg, 10 µg, 15 µg & 20 µg) of C5 compound isolated from the petals ofHibiscus rosa sinensis.IR absorptions peaks reveals the presence of functional groups alcohols, phenols, α,β unsaturated aldehyes, ketones and alkanes. The structure of compound was characterized as Hibiscetin-3-glucoside (C21H20O14) by Mass spectroscopy and NMR. The study emphasized flavanoid compounds have effective scavenging activities which may be due to its phenolics and flavonoid contents and can be used as anticancer agents.
关键词：Flavanoid;Antioxidant;DNA protector activity;IR;NMR;Hibiscetin-3-glucoside