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标题：PHYTOCHEMICAL INVESTIGATIONS AND ANTIMICROBIAL ACTIVITIES OF GLYCYRRHIZA GLABRA (LINN.)
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作者：Muhammad Mubarak ; Ahmad Hussain ; Iftikhar Jan 等
期刊名称：Fresenius Environmental Bulletin
印刷版ISSN：1018-4619
出版年度：2020
卷号：29
期号：1
页码：251-259
语种：English
出版社：PSP Publishing
摘要：The ethnobotanical important wild medicinal plant Glycyrrhiza glabra (linn) was evaluated to determine various phytochemical constituents, antioxidant activity, elemental composition and antibacterial activity. The stem, roots and leaves were screened to obtained crude methanol (MeOH), chloroform (CHCh), ethyl acetate (EtOAc), n-butanol (BtOH) and aqueous (AQ) fractions. Results of phytochemical analysis divulged the presence of promising amount of total phenolic (159.56 mg GAE 100 g"1), total tannins (95.42 mg GAE 100 g-1), total fla- vonoids content (94.96 mg QE 100 g"1) in MeOH extract of root and leaves while lowest value was observed in CHCl3 fraction of stem (57.76 mg GAE 100 g-1), leaves (46.73 mg GAE 100 g-1) and root (44.60 mg QE 100 g-1). Remarkable antioxidant potential was observed in MeOH extract (80.58%) of root and trivial amount was found in CHCl3 fraction (56.77%) of leaves. Micro-minerals analysis reveals that lead (0.291 mg Kg-1), cadmium (0.780 mg Kg1), chromium (0.172 mg Kg-1) and cobalt was found maximum in root parts whereas iron (414.0 mg Kg- 1), zinc (68.33 mg Kg-1) and copper (60.33 mg Kg-1) was recorded in leaves. The antibacterial activity determine by well diffusion method divulges that all the extracts shows notable inhibitory activity against Proteus mirabilis, Escherichia coli and Agrobacterium tumefaciens.
关键词：Glycyrrhiza glabra;antioxidant activity;total flavonoids content antibacterial activity