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标题：Economic evaluation of a randomized controlled trial of an intervention to reduce office workers’ sitting time: the "Stand Up Victoria" trial
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作者：Gao L ; Flego A ; Dunstan DW 等
期刊名称：Scandinavian journal of Work, Environment and Health
印刷版ISSN：0355-3140
出版年度：2018
卷号：44
期号：5
页码：503-511
DOI：10.5271/sjweh.3740
语种：English
出版社：National Board of Occupational Safety and Health
摘要：Objectives This study aimed to assess the economic credentials of a workplace-delivered intervention to reducesitting time among desk-based workers.Methods We performed within-trial cost-efficacy analysis and long-term cost-effectiveness analysis (CEA) andrecruited 231 desk-based workers, aged 24–65 years, across 14 worksites of one organization. Multicomponentworkplace-delivered intervention was compared to usual practice. Main outcome measures including totaldevice-measured workplace sitting time, body mass index (BMI), self-reported health-related quality of life(Assessment of Quality of Life-8D, AQoL-8D), and absenteeism measured at 12 months.Results Compared to usual practice, the intervention was associated with greater cost (AU$431/person),benefits in terms of reduced workplace sitting time [-46.8 minutes/8-hour workday, 95% confidence interval(CI): -69.9– -23.7] and increased workplace standing time (42.2 minutes/8-hour workday, 95% CI 23.8–60.6).However, there were no significant benefits for BMI [0.148 kg/m 2 (95% CI-1.407–1.703)], QoL-8D [-0.006(95% CI -0.074–0.063)] and absenteeism [2.12 days (95% CI -2.01–6.26)]. The incremental cost-efficacy ratios(ICER) ranged from AU$9.94 cost/minute reduction in workplace sitting time to AU$13.37/minute reductionin overall sitting time. CEA showed the intervention contributed to higher life year (LY) gains [0.01 (95% CI0.009–0.011)], higher health-adjusted life year (HALY) gains [0.012 (95% CI 0.0105 – 0.0135)], and higher netcosts [AU$344 (95% CI $331–358)], with corresponding ICER of AU$34 443/LY and AU$28 703/HALY if theintervention effects were to be sustained for five-years. CEA results were sensitive to assumptions surroundingintervention-effect decay rate and discount rate.Conclusions The intervention was cost-effective over the lifetime of the cohort when scaled up to the nationalworkforce and provides important evidence for policy-makers and workplaces regarding allocation of resourcesto reduce workplace sitting.
关键词：cost-effectiveness analysis; cost-efficacy; economic evaluation; evaluation; intervention; office worker; productivity; randomized controlled trial; RCT; sit-stand workstation; sitting; sitting time; Stand-Up Victoria; workplace intervention