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标题：The effect of almonds consumption on blood pressure: A systematic review and dose-response meta-analysis of randomized control trials
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作者：Zhe Li ; Akshaya Srikanth Bhagavathula ; Mitchell Batavia 等
期刊名称：Journal of King Saud University - Science
印刷版ISSN：1018-3647
出版年度：2020
卷号：32
期号：2
页码：1757-1763
DOI：10.1016/j.jksus.2020.01.013
语种：English
出版社：Elsevier
摘要：AbstractAlmond is rich in antioxidants and phytochemicals such as methylquercetin, protocatechuic acid, catechin, flavonoids, p-hydroxybenzoic acid, resveratrol, vanillic acid, and kaempferol. The aim of the present study was to systematically review and dose-response meta-analyses the effects of almond consumption on systolic and diastolic blood pressure (SBP/DBP), respectively, in Randomized Controlled Trials (RCTs). A systematic search was performed in PubMed/MEDLINE, web of sciences and SCOPUS by 2 researchers, independently to identify randomised controlled trials up to July 2019. There were no time or language restrictions. PRISMA guidelines were followed in conducting this meta-analysis. Fifteen studies with 21 arms, containing 853 participants, reported SBP as an outcome measure. Pooled results showed significant reduction in SBP (WMD: −0.90 mmHg, 95% CI: −1.74, −0.06, Pheterogeneity = 0.94) by almond intervention. There is no significant effect from almond consumption on DBP (WMD: 0.67 mmHg, 95% CI: −1.93, 0.60, Pheterogeneity = 0.001). Meta-regression analysis showed dose of used almond (g/d) as source of heterogeneity between results of DBP. In conclusion results of this meta-analysis showed reduce effect of Almonds on systolic blood pressure.
关键词：Almond;Systolic blood pressure;Diastolic blood pressure;Meta-analysis