文章基本信息

标题：Extraction of polysaccharide from lotus leaf and its anticancer effect
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作者：Ma Yisi ; Liu Daiyao ; Zhu Kun 等
期刊名称：Journal of King Saud University - Science
印刷版ISSN：1018-3647
出版年度：2020
卷号：32
期号：2
页码：1702-1706
DOI：10.1016/j.jksus.2020.01.004
语种：English
出版社：Elsevier
摘要：AbstractThe selenium-enriched lotus leaf sclerotium mycelium fermented in 20 L bio-tank was used as raw material to optimize the extraction process of selenium polysaccharide in mycelium and analyze the structure of water-soluble selenium polysaccharide through anti-cancer effect. The optimal extraction conditions of selenium polysaccharide were obtained by experiment and Box-Behnken design method: extraction time was 50 min, extraction temperature was 83 °C, ratio of material to liquid was 1:130 (g:mL), extraction times were 2 times. It is 44.62%, which is 0.02% higher than the predicted value. At this time, the selenium content in the polysaccharide reaches 31.9 μg/g. The purified selenium polysaccharide is analyzed for anticancer effect, which has proliferation inhibition effect on various human cancer cells and inhibits tumor in vivo. Growing.
关键词：Lotus leaf pleated umbrella;Mycelium;Selenium polysaccharide;Response surface analysis;Anticancer effect