文章基本信息

标题：Effects of Monocular Perceptual Learning on Binocular Visual Processing in Adolescent and Adult Amblyopia
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作者：Li Gu ; Siyuan Deng ; Lei Feng 等
期刊名称：iScience
印刷版ISSN：2589-0042
出版年度：2020
卷号：23
期号：2
页码：1-21
DOI：10.1016/j.isci.2020.100875
语种：English
出版社：Elsevier
摘要：SummaryRe-establishing normal binocular visual processing is the key to amblyopia recovery beyond the critical period of visual development. Here, by combining perceptual learning, behavioral testing, and steady-state visually evoked potentials (SSVEPs), we examined how monocular perceptual learning in the amblyopic eye could change binocular visual processing in the adolescent and adult amblyopic visual system. We found that training reduced the interocular difference between amblyopic and fellow eyes and increased the amplitude of a binocular SSVEP component, with a significant negative correlation between the two measures. Our results demonstrate that training in the amblyopic eye primarily improves binocular rather than monocular visual processing in the amblyopic visual system, suggesting that behavioral training could potentially address key neural deficits in adolescent and adult amblyopia.Graphical AbstractDisplay OmittedHighlights•PL reduced the interocular difference•PL increased the amplitude of a binocular SSVEP component•Training in the amblyopic eye improves binocular visual processingBiological Sciences; Behavioral Neuroscience; Sensory Neuroscience