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标题：Comparative assessment of total phenolic content and in vitro antioxidant activities of bark and leaf methanolic extracts of Manilkara hexandra (Roxb.) Dubard
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作者：Sumana Dutta ; Sanjib Ray
期刊名称：Journal of King Saud University - Science
印刷版ISSN：1018-3647
出版年度：2020
卷号：32
期号：1
页码：643-647
DOI：10.1016/j.jksus.2018.09.015
语种：English
出版社：Elsevier
摘要：AbstractManilkara hexandrais a traditionally used medicinal plant.The aim of the present study was to analyzein vitroantioxidant potentials of the methanolic leaf (LMEMH) and bark (BMEMH)extracts ofM. hexandrain relation to total phenolics. Here,in vitroantioxidant activities of the extracts were tested through 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging, ferric ion reducing antioxidant power (FRAP), hydroxyl radical scavenging (HRS), and the total antioxidant activity (TAC) assays. The EC50of DPPH free radical scavenging with ascorbic acid, LMEMH, and BMEMH were calculated as 19.06 ± 2.2, 46.62 ± 6.13, and 88.66 ± 24.07 µg/mL respectively. The EC50of the Fe3+ ion reduction by ascorbic acid, LMEMH, and BMEMH were calculated respectively as 54.06 ± 5.00, 147.45 ± 22.46 and 480.34 ± 91.65 µg/mL. The LMEMH shows more HRS activity and the total phenolic content than the BMEMH. In conclusion, the leaf methanolic extract ofM. hexandrahas the comparatively morein vitroantioxidant potentials and total phenolics content than its bark methanolic extract.
关键词：Antioxidant;DPPH;FRAP;Reactive oxygen species;Manilkara hexandra